EARLYCDT-LUNG
- A simple physician-ordered blood test to aid in risk assessment and the early detection of lung cancer in high-risk patients.
- EarlyCDT-Lung detects the body’s immune response, in the form of autoantibodies (or immuno-biomarkers), to antigens produced by solid-tumor cells.
- EarlyCDT-Lung aids in risk assessment and early cancer detection by using a panel of tumor antigens that are selected for their involvement in the development of lung cancer.
- In healthy individuals, the immune system does not produce antibodies against normal tissue antigens. However, when cancer develops, cancer cells produce proteins with antigens that are abnormal or in some way modified from those found in normal tissue.
- The immune system detects these antigens and reacts by producing an abundance of autoantibodies that circulate in the bloodstream. As these autoantibodies form and circulate in the body at all stages of the disease including during Stages I and II, the earliest stages of lung cancer, their measurement signifies the presence of cancerous cells. The Oncimmune immuno-biomarker platform provides increased sensitivity while maintaining higher levels of specificity than other single or multiple antigen tests.
- Elevation of any one of the seven immuno-biomarkers above a predetermined cutoff value suggests that a tumor might be present.
- Risk assessment and early detection of lung cancer in asymptomatic high-risk patient populations are the primary benefits of EarlyCDT-Lung. It is also used as a follow-up test for high-risk patients who have indeterminate lung nodules identified by CT.
- Used in conjunction with diagnostic imaging, EarlyCDT-Lung has the potential to aid in the identification of lung cancer at a very early stage when treatment can be most successful.
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